Drug Daily

What is it? Benign prostatic hyperplasia (previously known as prostate adenoma) – the very first common urological disease in men after fifty. In the prostate formed nodes of various sizes and shapes, causing urination disorders and a variety of complications that threaten the life of the patient.

Causes. The emergence and development of BPH depends on many factors. First of all, this is a violation of age-related metabolism of male sex hormone – testosterone and increase estrogen levels. And it is important not only to the concentration of hormones in the blood, and their ability to live within the prostate.

BPH develops slowly, over decades of microscopic nodules and leads to a significant increase in the prostate. In normal prostate weighs about 20 grams, and in patients with BPH, it reaches 100 g (some – 250-300).

BPH Symptoms. Accepted separate course of the disease into three stages:

Read the rest of this entry »

Benign prostatic hyperplasia (BPH) – one of the most common diseases of older men. This benign tumor is detected in 50% of men aged 50 years and at 80-90% – in the age of 80 years. There are more than 23 million men with symptomatic BPH. In the US the number of registered patients with BPH is more than 500 thousand people. Therefore, it becomes clear not only medical but also social value of the whole range of problems associated with this disease

The development of BPH is due to age-related changes in the balance of sex hormones in the male body. As a result of hormonal imbalance in prostate tumor development, which is a classic example of the target organs for sex hormones.

The pathogenesis of BPH is the dysfunction of the bladder.

At international meetings on BPH (Paris, 1993, 1997, 2000, Monaco, 1995) approved by the questionnaire, known as “the International System of evaluation of symptoms in diseases of the prostate gland” (IPSS), in accordance with which to assess the scale of discrete points in the existence and extent of severity of the following 7 symptoms: incomplete emptying of the bladder, frequent urination, intermittent urination, the presence of peremptory impulses, sluggish stream of urine, delayed start of urination, night thamuria. These manifestations of the disease have a significant negative impact on the life of the patient, actually lead to a deterioration in quality of life.

The clinical picture and course of the disease depends primarily on the degree of disturbance of micturition. It must be borne in mind that the emergence and development infravesical obstruction in BPH is defined by two components: static – as a result of mechanical compression of the urethra of benign prostate tissue (compression) and dynamic, which is due to adrenergic hyperactivity of the bladder neck, prostatic urethra and the Department of prostate (constriction).

Read the rest of this entry »